腦科學系統平台
Neuroscience research platform
採用頭部外傷、腦中風、阿茲海默症動物模式，以micro-CT及MRI影像分析結構變化，以Y行迷宮、八爪迷宮、被動制約、Rotarod設備測試認知及運動功能。MRI實驗是與國家衛生研究院合作，這是以頭部外傷後3天到9個月的影像觀察結果。以DTI觀察白質損傷、以T2WI觀察腦部體積變化、以T1WI加入顯影劑觀察BBB通透性。影像及神經行為觀察分析之後，取得腦組織之後進行組織學、細胞學及分子生物學的分析。
Utilizing traumatic brain injury, stroke, Alzheimer's disease rat models for micro-CT and MRI imaging analysis of structural changes and cognitive and motor function testing with Y-maze, radial maze, passive avoidance, and Rotarod equipment. MRI experiments are conducted in collaboration with the Taiwan National Health Research Institutes, focusing on imaging observations from 3 days to 9 months after brain trauma. DTI is used to observe white matter damage, T2WI for brain volume changes, and T1WI with contrast agents to measure BBB permeability. After imaging and neurobehavioral analysis, brain tissue is collected for histological, cytological, and molecular biology analysis.
