急診系統平台
Emergency research platform
我們致力於探討急重症醫學中的關鍵病理機制，重點聚焦於多重性創傷（含創傷性腦損傷合併失血性休克）、急性缺氧（高山症）及環境毒物中毒（一氧化碳中毒）等急診臨床模擬模式。結合生理功能監測與分子生物技術，本平台深入研究急性應激下心、腦、肺、腸等多器官損傷之演變，並探討腸–腦軸交互作用、粒線體功能障礙及細胞死亡路徑之關鍵角色。藉由建立高穩定性的動物模型，我們為急重症藥物開發、器官保護策略與臨床救治轉譯提供卓越的科研資源與合作環境。
Our platform is dedicated to investigating the critical pathological mechanisms of acute and life-threatening conditions, with a primary focus on polytrauma (TBI combined with hemorrhagic shock), acute hypobaric hypoxia (altitude sickness), and carbon monoxide poisoning. By integrating physiological monitoring with advanced molecular biology, we examine the progression of multi-organ dysfunction across the brain, heart, lungs, and gastrointestinal tract, specifically exploring the gut-brain axis, mitochondrial dysfunction, and programmed cell death pathways. Through the establishment of robust and clinically relevant animal models, we provide premier research resources and collaborative opportunities for the development of organ-protective strategies and the advancement of emergency medicine clinical translation.
