謝俊民顧問

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期刊論文

  1. Jiunn-Min Shieh(1), Yih-Jeng Tsai, Ming-Chieh Ma, Chih-Li Chen, Wen-Bin Wu. The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp. Scientific Reports 14 (1), 7559, 2024.

  2. Shih-Lun Chang, Yih-Jeng Tsai, Jiunn-Min Shieh, Wen-Bin Wu. The novel thromboxane prostanoid receptor mediates CTGF production to drive human nasal fibroblast self-migration through NF-kB and PKCδ-CREB signaling pathways. Journal of Cellular Physiology 239 (9), e31390, 2024.1. 

  3. Shih-Hsuan Huang, Hung-Chia Hsieh, Jiunn-Min Shieh, Wou-Chou Su, Yi-Ching Wang. Downregulation of microRNA-326 enhances ZNF322A expression, transcriptional activity and tumorigenic effects in lung cancer. Biofactors 50 (1) 214-227, 2024.

  4. Jiunn-Min Shieh(1), Ting-Wei Chang, Jing-He Wang, Song-Ping Liang, Pei-Lu Kao, Liang-Yi Chen, Chia-Jui Yen, Yun-Ju Chen, Wen-Chang Chang, Ben-Kuen Chen. RNA-binding protein-regulated fibronectin is essential for EGFR-activated metastasis of head and neck squamous cell carcinoma. The FASER journal 37 (10), e23206, 2023.

  5. Ming-Hung Chang, Kuo-Hwa Chiang, Jiunn-Min Shieh , Kuo-Chen Cheng, Chung-Han Ho. Analysis of non-small cell lung cancer with miliary lung metastasis in patients harboring epidermal growth factor receptor mutations. Scientifc Reports, 12(1), 18182, 2022.

  6. Sheng-Yeh Shen, Chang-Wen Chen, Tu-Chen Liu, Cheng-Yi Wang, Ming-Huang Chiu, Yi-Jen Chen, Chou-Chin Lan, Jiunn-Min Shieh, Chia-Ma Lin, Shao-Hao Wu, Hao-Chien Wang, Lala Yang, Maartrn JHI Beekman. SABA prescriptions and asthma management practices in patients treated by specialists in Taiwan: Results from the SABINA III study. Journal of the Formosan Medical Association 121 (12), 2527-2537, 2022.

  7. Wen-Chin Ko, Jiunn-Min Shieh,Wen-bin Wu.P38 MAPK and Nrf2 Activation Mediated Naked Gold Nanoparticle Induced Heme Oxygenase-1 Expression in Rat Aortic Vascular Smooth Muscle Cells.Arch Med Res.2020 Jul;51(5):388-396. doi: 10.1016/j.arcmed.2020.04.015. Epub 2020 May 11.

  8. Kuo-Hwa Chiang(1), Jiunn-Min Shieh(1), Chih-Jie Shen, Ting-Wei Chang, Pei-Ting Wu,Jinn-Yuan Hsu, Jhih-Peng Tsai, Wen-Chang, Ben-Kuen Chen. Epidermal growth factor-induced COX-2 regulates metastasis of head and neck squamous cell carcinoma through upregulation of angiopoietin-like 4. Cancer science 29 March 2020. Volume 111, Issue 6,2004-2015.

  9. Jiunn-Min Shieh, Hui-Yun Tseng, Fang Jung, Shih-Hsing Yang, Jau-Chen Lin. Elevation of IL-6 and IL-33 Levels in Serum Associated with Lung Fibrosis and Skeletal Muscle Wasting in a Bleomycin-Induced Lung Injury Mouse Model. Mediators of Inflammation, vol. 2019, > Article ID 7947596, 12 pages, 2019.

  10. Jiunn‐Min Shieh, Yih‐Jeng Tsai, Jessie Chao‐Yun Chi, Wen‐Bin Wu. TGFβ mediates collagen production in human CRSsNP nasal mucosa‐derived fibroblasts through Smad2/3‐dependent pathway and CTGF induction and secretion. J Cell Physiol. 2018;1–11.

  11. Huey-Ming Lo, Ming-Chieh Ma, Jiunn-Min Shieh, Wen-Bin Wu. Naked physically synthesized gold nanoparticles affect migration, mitochondrial activity, and proliferation of vascular smooth muscle cells.International Journal of Nanomedicine 2018:13 3163–3176.

  12. Jen-Yu Hung, Shyh-Ren Chiang, Kuan-Ting Liui, Ming-Ju Tsai, Ming-Shyan Huangi, Jiunn-Min Shieh, Meng-Chi Yen, Ya-Ling Hsu. Overexpression and proliferation dependence of acyl‑CoA thioesterase 11 and 13 in lung adenocarcinoma. Oncology Letters 14: 3647-3656, 2017

  13. Jiunn-Min Shieh, Yen-An Tang, Fu-Han Hu, Wei-Jan Huang, Ying-Jan Wang, Jayu Jen, Sheng-You Liao, Ying-Hung Lu, Ya-Ling Yeh, Tseng-Wei Wang, Pinpin Lin and Yi-Ching Wang. A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against non small-cell lung cancer. Int J Cancer. 2017 May 15; 140(10): 2375-2386 doi:10.1002/ijc.30664.

  14. Y-H Liao, K-H Chiang, J-M Shieh, C-R Huang, C-J Shen, W-C Huang,B-K Chen. Epidermal growth factor-induced ANGPTL4 enhances anoikis resistance and tumor metaststasis in head and neck squamous cell carcinoma. Oncogene. 2017;36: 2228-2242.

  15. Ching-Min Wang , Chao-Tien Hsu, Ho-Shan Niu, Chin-Hong Chang, ,Juei-Tang Cheng*, Jiunn-Min Shieh* Lung damage induced by hyperglycemia in diabetic rats: The role of signal transducer and activator of transcription 3 (STAT3). J Diabetes Complicat. 2016; 30: 1426-1433.(I.F.3.005,62/128)

  16. Chih-Cheng Lai, Jiunn-Min Shieh, Shyh-Ren Chiang, Kuo-Hwa Chiang,Shih-Feng Weng,Chung-Han Ho, Kuei-Ling Tseng,Kuo-Chen Cheng. The outcomes and prognostic factors of patients requiring prolonged mechanical ventilation. Sci Rep. 2016 Jun 14; 6: 28034

  17. Y-H Liao, K-H Chiang, J-M Shieh, C-R Huang, C-J Shen, W-C, Huang,B-K Chen. Epidermal growth factor-induced ANGPTL4 enhances anoikis resistance and tumour metastasis in head and neck squamous cell carcinoma. Oncogene 2016; 1-15.

  18. Yao-Jian Hsieh,Ying-Chieh Su,Shyh-Ren Chiang,Khin-Than Win,Chia-Hui Chen,Jiunn-Min Shieh. Tracheal Fibroepithelial Polyp Treated with Endobronchial Cryotherapy Combined with Argon Laser: A case Report and Literature Reviw. Thorac Med 2016; 31: 288-293.

  19. Kuei-Ling Tseng, Jiunn-Min Shieh(1) , Kuo-Chen Cheng, Kuo-Hwa Chiang, Shyh-Ren Chiang, Shiann-Chin Ko, Ai-Chin Cheng, Chin-Ming Chen. Tracheostomy versus Endotracheal Intubation Prior to Admission to a Respiratory Care Center: A Retrospective Analysis. Int J Gerontol. 2105;9 :151-155.
     
  20. Tsung-Hsuan Lai, Jiunn-Min Shieh, Chih-Jen Tsou, Wen-Bin Wu. Gold nanoparticles induce heme oxygenase-1 expression through Nrf2 activation and Bach 1 export in human vascular endothelial cells. Int. J. Nanomedicine 2015;10:5925-5939.

  21. Jen-Yu Hung, Shyh-Ren Chiang, Ming-Ju Tsai, Ying-Ming Tsai, Inn-Wen Chong, Jiunn-Min Shieh, Ya-Ling Hsu. LIGHT is a Crucial Mediator of Airway Remodeling. J.Cell. Physiol. 2015 May;230(5):1042-53.

  22. Yi-Chieh Yang, Yen-An Tang, Jiunn-Min Shieh, Ruo-Kai Lin, Han-Shui Hsu, Yi-Ching Wang. DNMT3B Overexpression by deregulation of FOXO3a-Mediated Transcription Repression and MDM2 Overexpression in Lung Cancer. J Thorac Oncol. 2014;9: 1305-1315.(Co- first authors)

  23. Jiunn-Min Shieh, Chih-Jie Shen, Wei-Chiao Chang, Hung-Chi Cheng, Ya-Yi Chan, Wan-Chen Huang, Wen-Chang Chang, Ben-Kuen Chen. An Increase in Reactive Oxygen Species by Deregulation of ARNT Enhances Chemotherapeutic Drug-Induced Cancer Cell Death. PLoS one, 2014;9(6): e99242.

  24. Jiunn-Min Shieh, Yih-Jeng Tsai, Chih-Jen Tsou, Wen-Bin Wu.CXCL1 Regulation in Human Pulmonary Epithelial Cells by Tumor Necrosis Factor. Cell Physiol. Biochem. 2014;34:1373-1384.

  25. S-C. Hsing, S-F. Weng, K-C. Cheng, J-M. Shieh, C-H. Chen, S-R. Chiang, J-J. Wang. Increased risk of pulmonary tuberculosis in patients with previous non-tuberculous mycobacterial disease. Int. J. Tuberc. Lung Dis. 2013,17(7):928-933.

  26. Jiunn-Min Shieh, Yen-An Tang, Tsung-Han Yang, Chih-Yi Chen, Han-Shui Hsu, Yi-Hung Carol Tan, Ravi Salgia, Yi-Ching Wang*. Lack of Association of C-Met-N375S Sequence Variant with Lung Cancer Susceptibility and Prognosis. Int. J. Med. Sci. 2013; 10(8):988-994

  27. Jiunn-Min Shieh, Yung-Chan Chen, Yin-Chao Lin, Jia-Ni Lin, Wei-Chih Chen,Yang-Yuan Chen, Chi-Tang Ho, Tzong-Der Way. Demethoxycurcumin Inhibits Energy Metabolic and Oncogenic Signaling Pathways through AMPK Activation in Triple-Negative Breast Cancer Cells. J. Agric. Food Chem. 2013, 61, 6366-6375.
     
  28. Shian-Chih Ko*, Chi-Ruei Huang*, Jiunn-Min Shieh, Jhen-Hong Yang, Wen-Chang Chang, Ben-Kuen Chen. Epidermal Growth Factor Protects Squamous Cell Carcinoma against Cisplatin-Induced Cytotoxicity through Increased Interleukin-1β Expression. PLoS one, 2013,8(2): e55795

  29. Jia-Yang Chen, Yen-An Tang, en-Shan Li, Yu-Ching Chiou, Jiunn-Min Shieh*, Yi-Ching Wang*. A Synthetic Podopyllotoxin Devirative Exerts Ant-Cancer Effects by Inducing Mitotic Arrest and Pro-Apoptotic ER Stress in Lung Cancer Preclinical Models. PLoS one, 2013, April: e62082. (Corresponding author)
     
  30. Huey-Ming Lo, Jiunn-Min Shieh, Chih-Li Chen, Chih-Jen Tsou, Wen-Bin Wu. Vascular Endothelial Growth Factor Induces CXCL1 Chemokine Release via JNK and PI-3K-Dependent Pathways in Human Lung Carcinoma Epithelial Cells. Int. J. Mol. Sci. 2013,14, 10090-10106.

  31. Jiunn-Min Shieh, Tzu-Tang Wei, Yen-An Tang, Sin-Ming Huang, Wei-Ling Wen, Mei-Yu Chen, Hung, Chi Cheng ,- Santosh B. Salunke, Ching-Shih Chen, Pinpin Lin, Chien-Tien Chen, Yi-Ching Wang. Mitochondrial Apoptosis and FAK Signaling Disruption by a Novel Histone Deacetylase Inhibitor, HTPB, in Antitumor and Antimetastatic Mouse Models. PLoS one, 2012;7,issue 1,e30240.

  32. Hung-Jen Tang, Yin-Ching Chung, Wen-Chien Kp, Chi-Chung Chen, Jiunn-Min Shieh, Chung-Hua Chen, Nan-Yao Lee, Shyh-Ren Chiang. Comparative evaluation of intratracheal colistimethate sodium, imipenem, and meropenem in BALB/c mice with carbapenem-resistant Acinetobacter baumannii pneumonia. Int J Infect Dis, 2012; 1,16(1):e34-e40.

  33. Jiunn-Min Shieh, Tsan-Hwang Cheng, Ming-Der Shi, Pei-Fen WU, Yi Chen, Shian-Chin Ko, Yuan-Wei Shih. α-Tomatine Suppresses Invasion and Migration of Human Non-Small Cell Lung Cancer NCI-H460 Cells Through Inactivation FAK/PI3K/Akt Signaling Pathway and Reducing Binding Activity of NF-κB. Cell Biochem Biophys, 2011; 60,297-310.
     
  34. Nai-Ding Liao, Jiunn-Min Shieh, Wen-Ying Lee.Diagnostic Value of Metabolic Phenotypes in Malignant Pleural Effusions: expression of GLUT1 and CAIX by immunocytochemistry. Cancer Cytotopatho 2011,published online (I.F:2.77, ranking 21/76=28% on pathology)

  35. Jiunn-Min Shieh, Tur-Fu Hung, Chi-Feng Hung, Kuan-Hsien Chou, Yih-Jeng Tsai and Wen-Bin Wu. Activation of c-Jun N-terminal kinase is essential for mitochondrial membrane potential change and apoptosis induced by doxycycline in melanoma cells. British Journal of Pharacology, 2010; 160:1171-1181.

  36. Cheng-Ta Yang, Jen-Yu Hung,Chun-Liang lai, Hsin-Chia Hung, Yung-Fa Lai, Meng-Chih Lin, Jiunn-Min Shieh, Ming-Shyan Huang. Gefitinib as First- Line Therapy for Advanced or Metastatic NSCLC Patients in Southern Taiwan. Kaohsiung J Med Sci. 2010, 26:1-7.

  37. Pin-Liang Chen, *Jiunn-Min Shieh, Shiann-Chin Ko. Two Synchronous Primary Lung Cancers: A case Report. Thorac Med 2010; 25: 85-90.

  38. Jiunn-Min Shieh, Hung-Tsung Wu, Kai-Chun Cheng, Juei-Tang Cheng. Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen synthesis via a PKCζ-Akt-GSK3β pathway in hepatic cells. J. Pineal Res. 2009; 47:339-344.

  39. Jiunn-Min Shieh, Tai-An Chiang, Wen-Teng Chang, Chang-Hung Chao, Yi-Chieh Lee, Guan-YuHung, You-Xin Shih, Yuan-Wei Shih. Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activitis of NF-κB and AP-1 via ERK signaling pathway in A549 human lung cancer cells. Mol Cell Biochem. 2009; 335,181-193.

  40. Yuan-Wei Shih, Jiunn-Min Shieh, Pei-FenWu, Yi-Chieh Lee, Yi-Zhi Chen, Tai-An Chiang.α-Tomatine inactivates PI3K/Akt and ERK signaling pathways in human lung adenocarcinoma A549 cells: Effect on metastasis. Food and Chemical Toxicology. 47(2009) 1985-1995.(sci)

  41. Ching-Yih Lin, Shih-Bin Su, Chih-Ching Chang, Tsung-Ming Lee, Jiunn-Min Shieh, How-Ran Guo. The Association Between Chlamydia Pneumoniae and Metabolic Syndrome in Taiwanese Adults. Southern Medical Journal.2009; 102(12)

  42. Chi-Feng Hung, Tur-Fu Huang, Bing-Huei Chen, Jiunn-Min Shieh, Pi-Hui Wu and Wen-Bin Wu. Lycopene Inhibits TNF-alfa-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion. European Journal of Pharmacology :volume 586, issues 1-3, 31 May 2008, P275-282.

  43. Hsin-Kai Huang, Chih-Hsiung Chen, Shian-Chih Ko, Kuo-Chen Cheng, Jiunn-Min Shieh, Kuo-Hwa Chaing. Anterior Mediastinal Type B3 Invasive Thymoma with Multiple Intrapulmonary Metastasses: A Case Report. Thorax Med 2008; 23: 355-361.

  44. Chih-Hsiung Chen, Kun-Ming Chung, Jiunn-Min Shieh, Shian-Chin Ko,Hsiu-Nien Shen Kuo-Chen Cheng. Hemophagocytic Syndrome Associated with Diffuse Large-B-Cell Lymphoma: A case Report. Thorac Med 2008; 23: 55-60.

  45. Su, Cheng-Chuan, Shieh Jiunn-Min, Li-Chien-Feng.Endobronchial metastatic breast carcinoma clinically, histologically, histologically and cytologically mimicking pulmonary small cell carcinoma. Pathology: volume 39, Number 2, April 2007, PP. 269-271 (3)

  46. Shian-Chin Ko, Jian-Fong Li, Jiunn-Min Shieh. Mycobacterium avium complex(MAC) Lung Abscess Successful Treated with Traditional Antituberculosis Therapy. Thorac Med 2007; 22( 6 suppl): 87. 

  47. Shian-Chin Ko, Yu-Feng Tian, Jiunn-Min Shieh. Drug Interaction between Rifampin and Cycloosporin in a Renal Transplant Recipient with Pulmonary Tuberculosis. Thorac Med 2007; 22( 6 suppl): 86. 

  48. Chih-Hsiung Chen, Kuo-Hwa Chiang, Shian-Chin Ko, Shyh-Ren Chiang, Kuo-Chen Cheng, Jiunn-Min Shieh. Anterior Mediastinal Type B3 Invasive  Thymoma with Multiple Intrapulmonary Metastases. Thorac Med 2007; 22( 6 suppl): 71

  49. Chih-Hsiung Chen, Tzu-Chieh Weng, Lien-Hui Hsu, Wei-Neng Lin Shyh-Ren Chiang, Jiunn-Min Shieh. Acute Pulmonary Embolism and Occult lUng Adenocarcinoma : A Case Report of Trousseau’s Syndrome. Thorax Med 2007; 22:243-248.

  50. Chih-Hsiung Chen, Jiunn-Min Shieh, Lien-Hui Hsu, Hsiu-Nien Shen Kuo-Chen Cheng, Shian-Chih Ko. Acute Respiratory Distress Syndrome Causes by Mycoplasma Pneumonia Infection: A case Report. Thorax Med 2007; 22:215-221.

  51. Wei-Neng Lin, Shian-Chin Ko, Chih-Hsiung, His-Hsing Yanf, Kuo-Chen Cheng,  *Jiunn-Min Shieh. Acute Pulmonary Edema Following Transjugular Intrahepatic Portosystemic Stent Shunt Creation in A Cirrhotic Patient: A Case Report. Thorac Med 2007; 22:259-264. (Corresponding author)

  52. Shian-Chin Ko, Mei-Chun Chou, Jiunn-Min Shieh. Acute Lung Injury Induced by Illegal Use of Ketamine Inhalation. Thorac Med 2006; 21( 6 suppl):152.

  53. Shian-Chin Ko, Mei-Chun Chou, Jiunn-Min Shieh. Acute Lung Injury Induced by Illegal Use of Ketamine Inhalation. Thorac Med 2006; 21( 6 suppl):152

  54. Shian-Chin Ko, Mei-Chun Chou, Jiunn-Min Shieh. Interlobar Pulmonary Sequestration in an Elderly Woman Incidentally Found by Three-Dimensional  Multi-dectector Computerized Tomography ( 3D MDCT) Angiography. Thorac Med 2006; 21( 6 suppl): 151

  55. Chih-Hsiung Chen, Lien-Hui Hsu,Shian-Chin Ko, Wei-Neng Lin, Jiunn-Min Shieh. Pleural-Based Pulmonary Arteriovenous Malformation: High Risk for Ultrasound-Guided Needle Biopsy. Thorac Med 2006; 21( 6 suppl): 104

  56. Shian-Chin Ko, Jiunn-Min Shieh. A Rare Case of Ethambutol-induced Toxic Epidermal Necrolysis ( TEN) in a Patient with Open Tuberculosis and Diabetic Neuropathy. Thorac Med 2006; 21( 6 suppl): 163 Chih-Hsiung Chen, Jiunn-Min Shieh. Lien-Hui Hsu, Kuo-Chen Cheng, Shian-Chin Ko, Acute Respiratory Distress Syndrome Associated with Mycoplasma Pneumoniae Infection: ACase Report. Thorac Med 2006; 21( 6 suppl): 164

  57. Gang-Yu Shen, Kuo-Hwa Chiang, Yao Fong, Jiunn-Min Shieh. Symptomatic Mediastinal Bronchogenic Cyst Mimicking Esophageal lesion in a Patient with Chronic cough-A case Report and Literature Review. Thorac Med 2006; 21: 362-368.

  58. Ming-Tai Wu, Wen-Liang Yu, Jiunn-Min Shieh, Kuo Chen Cheng. Isolated Cryptococcal Pleural Involvement in a Patient With Renal Tuberculosis. Thorac Med 2006; 21: 208-285

  59. Jiunn-Min Shieh, Kue-Lin, Zenth, Sia-Lin Din, et al. The Five Years’ Experences of Respiratory Care Center in Southern Taiwan. Thorac Med 2005; 20( 6 suppl): 79

  60. Kuo-Hwa Chiang, Gang-Yu Shen, Yao Fong, Jiunn-Min Shieh. Mediastinal Bronchogenic Cyst Presenting as Esophageal Lesion-A Case Report and Review of the literature. Thorac Med 2005; 20( 6 suppl): 109

  61. Lien-Hui Hsu, Shian-ChinKo, Kau-Chen Cheng,Yao Fong, Jinn-Ming Chang, Ching-Nan Lin, Jiunn-Min, Shieh. Coexistence of Carcinoid Tumor and Adenocarcinoma within the Esophageal Diverticulum Complicated with Empyema Thoracis—A case report. Thorac Med 2005; 20: 463-470.(Corresponding author )

  62. En-Chung Cheng, Yao-Fong, Kuo-Chen Cheng, Shih-Sung Chung, Jiunn-Min, Shieh. A Rare Case of Malignant Gastrointestinal Stromal Tumor of the Esophagus in a Patient with Chronic Cough. Thorac Med 2005; 20: 306-312. (Corresponding author)

  63. Chin-Ming Chen, Mei-Yi Sung, Kuo-Chen Cheng , Jiunn-Min Shieh. The Relationship between Body Mass Index and Prognosis in a Respiratory Care Center. J Emerg Crit Care Med. Vol.16, No.1, 2005; 9-17. (Corresponding author)

  64. Sheng-Chin Liao,Yung-Chih Cheng,Yo-Ching Wang, Chiung-Wen Wang, San-Ming Yang, Chun-Keung Yu, Chi-Chang Shieh, Kuo-Chen Cheng, Meng-Feng Lee, Shyh-Ren Chiang, Jiunn-Min Shieh, and Ming-Shi Chang . IL-19 Induced Th2 Cytokines and Was Up-regulated in Asthma patients. The Journal of Immunology, 2004, 173:6712-6718(sci)
     
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