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2021

  • Chi-Chun Chen, Liang-Jyun Hong, Jian-Yong Wang, Ching-Ping Chang. A robust bitmap-based real-time position tracking algorithm for rats in radial arm maze tests. Scientific Reports 2021 November 17;11(1):22447.
  • Chien-Ming Chao, Chien-Chin Hsu, Chien-Cheng Huang, Chung-Han Wang, Mao-Tsun Lin, Ching-Ping Chang*, Hung-Jung Lin*, Chung-Ching Chio*. Selective brain cooling achieves peripheral organs protection in hemorrhagic shock resuscitation via preserving the integrity of the brain-gut axis. International Journal of Medical Science. 2021 June; 18: 2920-2929.
  • Shu-Chun Kuo, Chung-Ching Chio, Chao-Hung Yeh, Jui-Ti Ma, Wen-Pin Liu, Mao-Tsun Lin, Kao-Chang Lin*, Ching-Ping Chang*. Mesenchymal stem cell-conditioned medium attenuates the retinal pathology in amyloid-b-induced rat model of Alzheimer's disease: underlying mechanisms. Aging Cell 2021 Mar 30:e13340. doi: 10.1111/acel.13340.
  • Yu-Wen Lin, Chin-Yu Chen, Jhih-Yuan Shih, Bor-Chin Cheng, Ching-Ping Chang, Mao-Tsun Lin, Zhih-Cherng Chen, Sudeshna Fisch, Wei-Ting Chang*. Dapagliflozin improves cardiac hemodynamics and mitigates arrhythmogenesis in mitral regurgitation-induced myocardial dysfunction. JAHA: Journal of the American Heart Association. 2021 Apr 6;10(7): e019274. doi: 10.1161/JAHA.120.019274.
  • Rong-Jane Chen, Yu-Hsuan Lee, Tzu-Hao Chen, Yu-Ying Chen, Ya-Ling Yeh, Ching-Ping Chang, Chien-Cheng Huang, How-Ran Guo, Ying-Jan Wang*. Carbon monoxide-triggered health effects: The important role of the inflammasome and its possible crosstalk with autophagy and exosomes. Achives Toxicology. 2021 Apr;95(4):1141-1159. doi: 10.1007/s00204-021-02976-7.
  • Chien-Cheng Huang, Tzu-Hao Chen, Chung-Han Ho, Yi-Chen Chen, Chien-Chin Hsu, Hung-Jung Lin, Jhi-Joung Wang, Ching-Ping Chang, How-Ran Guo. Increased risk of congestive heart failure following carbon monoxide poisoning. Circulation: Heart Failure 2021 Apr;14(4):e007267.
  • Pei‑Hsuan Lin, Kuan‑Hua Huang, Yu‑Feng Tian, Cheng‑Hsien Lin, Chien‑Ming Chao, Ling‑Yu Tang, Kun‑Lin Hsieh*, Ching‑Ping Chang*. Exertional heat stroke on fertility, erectile function, and testicular morphology in male rats. Scientific Reports 2021 Feb, 11:3539.
  • Tai PA, Chang CK, Niu KC, Lin MT, Chiu WT, Lin JW. Attenuation of Heat-Induced Hypothalamic Ischemia, Inflammation, and Damage by Hyperbaric Oxygen in Rats. J Neurotrauma. 2021 Apr 15;38(8):1185-1192.

2020

  • Chien-Chin Hsu, Chien-Cheng Huang, Lan-Hsiang Chien, Mao-Tsun Lin, Ching-Ping Chang*, Hung-Jung Lin*, Chung-Ching Chio*. Ischemia/reperfusion injured intestinal epithelial cells cause cortical neuron death by releasing exosomal microRNAs associated with apoptosis, necroptosis, and pyroptosis. Scientific Reports 2020 Sep; 10:14409
  • S.H. Lin, C.S. Chien,T.Y. Kuo, Y.H. Hsieh,W.H. Chin, J.W. Huang, C.P. Chang, T.M. Lee, H.T. Lee. Biomedical evaluation of vacuum plasma sprayed tantalum coatings processed by alkali treatment and alkali-heat treatment with different NaOH concentrations. Surface and Coatings Technology, December 15 2020, 403: 126400.
  • Chien-Ming Chao, Chun-Liang Chen, Ko-Chi Niu, Cheng-Hsien Lin, Ling-Yu Tang, Lieh-Sheng Lin, Ching-Ping Chang*. Hypobaric hypoxia preconditioning protects against hypothalamic neuron apoptosis in heat-exposed rats by reversing hypothalamic overexpression of matrix metalloproteinase-9 and ischemia. International Journal of Medical Science 2020 September 20;17(17):2622-2634.
  • Yu-Lin Wang, Jui-Chi Cheng, Ching-Ping Chang, Fong-Chin Su, Chi-Chun Chen. Individualized Running Wheel System with a Dynamically Adjustable Exercise Area and Speed for Rats Following Ischemic Stroke. Medical Science Monitor 2020; 26:e924411.
  • Chi-Chun Chen, Ching-Ping Chang. Development of a three-channel automatic climbing training system for rat rehabilitation after ischemic stroke. Braz J Med Biol Res. 2020;53(7):e8943. doi: 10.1590/1414-431X20208943. Epub 2020 June 10.
  • Chien-Chin Hsu, Ting-Wei Kuo, Wen-Pin Liu, Ching-Ping Chang , Hung-Jung Lin. Calycosin preserves BDNF/TrkB signaling and reduces post-stroke neurological injury after cerebral ischemia by reducing accumulation of hypertrophic and TNF--containing microglia in rats. J Neuroimmune Pharmacology. 2020 Jun;15(2):326-339.
  • Wen-Ching Ko, Cheng-Hsien Lin, Jie-Jen Lee, Ching-Ping Chang*, Chien-Ming Chao*. Therapeutic hypothermia protects against heat stroke-induced arterial hypotension via promoting left ventricular performance in rats. International Journal of Medical Science. 2020 February 10; 17: 525-535.
  • Hsu CC, Huang CC, Chien LH, Lin MT, Chang CP, Lin HJ, Chio CC. Ischemia/reperfusion injured intestinal epithelial cells cause cortical neuron death by releasing exosomal microRNAs associated with apoptosis, necroptosis, and pyroptosis. Sci Rep. 2020 Sep 1;10(1):14409.

2019

  • Cheng-Hsien Lin, Cheng-Chia Tsai, Tzu-Hao Chen, Ching-Ping Chang*, Hsi-Hsing Yang*. Oxytocin maintains lung histological and functional integrity to confer protection in heat stroke. Scientific Reports 2019 Dec ; 9: 18390. doi:10.1038/s41598-019-54739-1.
  • Chi-Chun Chen, Yu-Lin Wang, Ching-Ping Chang. Remarkable reduction in cerebral infarct volume in rat patients using an escalator-based rehabilitation mechanism. PlosOne. 2019 Oct 11;14(10):e0223820. doi: 10.1371/journal.pone.0223820. eCollection 2019.
  • Kuan-Hung Cho, Sheng-Min Huang, Ming-Jye Chen, Hsuan-Han Chiang, Chang-Hoon Choi, Richard Buschbeck, Ezequiel Farrher, N. Jon Shah, Ruslan Garipov, Ching-Ping Chang, Hsu Chang, and Li-Wei Kuo. Development and Integration of an Ultra-High-Strength Gradient System on a 3 T Clinical MRI for Small Animal Imaging. PLoS One. 2019 Jun 3; 14(6):e0217916. doi: 10.1371/journal.pone.0217916. eCollection 2019.
  • Cheng-Hsien Lin, Sheng-Hsien Chen, Ching-Ping Chang*, Kao-Chang Lin*. Hypothalamic impairment underlying heat intolerance in pregnant mice. Mol Cell Endocrinol. 2019 July 15; 492: 110439.
  • Yu-Ling Wang, Cheng-Hsien Lin, Chi-Chun Chen, Ching-Ping Chang, Kao-Chang Lin, Fong-Chin Su*, Willy Chou*. Exercise preconditioning attenuates neurological injury by preserving old and newly formed HSP-72-containing neurons in ischemic stroke rats. International J Medical Sciences. 2019 May 10;; 16(5):675-685. doi:10.7150/ijms.32962.
  • Mahmoud Z. Ibrahim, Ahmed A. D. Sarhan*, T. Y. Kuo, M. Hamdi, Farazila Yusof, C.S. Chien*, C.P. Chang, T. M. Lee. Advancement of the artificial amorphous-crystalline structure of laser cladded FeCrMoCB on nickel-free stainless-steel for bone-implants. Journal of Materials Chemistry and Physics. 2019 April 1. 227: 358-367.
  • Chi-Chun Chen, Ching-Ping Chang, and Chin-Lung Yang. An adaptive fall-free rehabilitation mechanism for ischemic stroke rat patients. Sci Rep. 2019 January 30; 9(1):984. doi: 10.1038/s41598-018-37282-3.
  • Cheng-Hsien Lin, Willie Lin, Yu-Chin Su, Yogi Cheng-Yo Hsuan, Yu-Chien Chen, Ching-Ping Chang, Willy Chou*,Kao-Chang Lin*. Modulation of parietal cytokine and chemokine gene profiles by mesenchymal stem cell as a basis for neurotrauma recovery. J Formos Med Assoc. 2019 Dec. 118 (12): 1661-1673.
  • Cheng-Chia Tsai, Hsing-Hsien Wu, Ching-Ping Chang, Cheng-Hsien Lin, Yang HH*. Calycosin-7-O-β-D-glucoside reduces myocardial injury in heat stroke rats. Journal of Formosan Medical Association. 2019 Mar. 118(3): 730-738.

2018

  • Chi-Chun Chen and Ching-Ping Chang. How to Modify the Forced Running Wheel for Ischemic Stroke Rehabilitation in Rats. Neuropsychiatry (London) 2018; 8(3), 1061–1072.
  • Wu HH, Huang CC, Chang CP, Lin MT, Niu KC*, Tian YF*. (2018) Hyperbaric oxygen preconditioning protects against liver ischemia/reperfusion injury by heat shock protein 70 overexpression. Medical Science Monitor 2018 November 12; 24: 8096-8104.
  • Hsing-Hsien Wu, Ko-Chi Niu, Cheng-Hsien Lin, Hung-Jung Lin, Ching-Ping Chang*, Chia-Ti Wang*. (2018) HSP70-mediated hyperbaric oxygen reduces brain and pulmonary edema and cognitive deficits in rats in a simulated high altitude exposure. Biomed Research International 2018 November 1; 2018:4608150. doi: 10.1155/2018/4608150.
  • Ching-Ping Chang, Yu-Yi Chan , Chien-Feng Li, Lan-Hsiang Chien , Song-Tay Lee , Ting-Feng Wu *. (2018) Deciphering the molecular mechanism underlying the inhibitory efficacy of Taiwanese local pomegranate peels against urinary bladder urothelial carcinoma. Nutrients. 10(5). pii: E543. doi: 10.3390/nu10050543.
  • Chou W, Liu YF, Lin CH,Lin MT, Chen CC, Chang CP*, Chio CC *. (2018) Exercise rehabilitation attenuates cognitive deficits in rats with traumatic brain injury by stimulating the cerebral HSP20/BDNF/TrkB signalling axis. Molecular Neurobiology 2018 Nov; 55(11):8602-8611.
  • Lin X, Zhao T, Lin CH, Zuo D, Ye Z, Lin S, WenS, Liu L, Lin MT, Chang CP*, Chao CM*. (2018). Melatonin provides protection against heat stroke-induced myocardial injury in male rats. Journal of Pharmacy and Pharmacology 70(6):760-767.
  • Lin X, Zhao T, Lin CH, Zuo D, Ye Z, Lin S, Wen S, Liu L, Lin MT, Chang CP, Chao CM. Melatonin provides protection against heat stroke-induced myocardial injury in male rats. J Pharm Pharmacol. 2018 Jun;70(6):760-767.
  • Chou W, Liu YF, Lin CH, Lin MT, Chen CC, Liu WP, Chang CP, Chio CC. Exercise Rehabilitation Attenuates Cognitive Deficits in Rats with Traumatic Brain Injury by Stimulating the Cerebral HSP20/BDNF/TrkB Signalling Axis. Mol Neurobiol. 2018 Nov;55(11):8602-8611.
  • Wu HH, Huang CC, Chang CP, Lin MT, Niu KC, Tian YF Heat Shock Protein 70 (HSP70) Reduces Hepatic Inflammatory and Oxidative Damage in a Rat Model of Liver Ischemia/Reperfusion Injury with Hyperbaric Oxygen Preconditioning. Med Sci Monit. 2018 Nov 12;24:8096-8104.

2017

  • Lin W, Hsuan YCY, Su YC, Lin CH, Lin MT, Chen ZH, Chang CP*, Lin KC*.(2017) CD34− human placenta-derived mesenchymal stem cells protect against heat stroke mortality in rats. Oncotarget 9(2):1992-2001. doi: 10.18632/oncotarget.23324.
  • Lin W, Hsuan YCY, Lin MT, Kuo TW, Lin CH, Su YC, Niu KC, Chang CP*, Lin HJ*. (2017) Human umbilical cord mesenchymal stem cells preserve adult newborn neurons and reduce neurological injury after cerebral ischemia by reducing the number of hypertrophic microglia/macrophages. Cell Transplantation 26(11): 1798-1810.
  • Lin HJ*, Hsu CC, Chio CC, Tian YF, Lin MT, Lin TW, Chang CH, Chang CP. (2017) Gamma-Secretase inhibitors attenuate neurotrauma and neurogenic acute lung injury in rats by rescuing the accumulation of hypertrophic microglia. Cellular Physiology and Biochemistry. 44:1726-1740.
  • Chio CC, Hsu CC, Tian YF, Wang, CH, Lin MT, Chang CP, Lin HJ*. (2017) Combined hemorrhagic shock and unilateral common carotid occlusion induces neurological injury in adult male rats. International J Medical Sciences. 14(13):1327-1334.
  • Chio CC, Lin HJ, Tian YF, Chen YC,Lin MT, Lin CH, Chang CP*, Hsu CC*.(2017) Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-κB/ IL-6/synapsin I axis in traumatic brain injury rats. J Neuroinflammation. 2017 Apr 24; 14(1):90. doi: 10.1186/s12974-017-0867-9
  • Lin X, Lin CH, Zhao T, Zuo D, Ye Z, Liu L, Lin MT. Quercetin protects against heat stroke-induced myocardial injury in male rats: Antioxidative and antiinflammatory mechanisms. Chem Biol Interact. 2017 Mar 1;265:47-54.
  • Chio CC, Lin HJ, Tian YF, Chen YC, Lin MT, Lin CH, Chang CP, Hsu CC. Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-κB/IL-6/synapsin I axis in traumatic brain injury rats. J Neuroinflammation. 2017 Apr 24;14(1):90.
  • Chio CC, Hsu CC, Tian YF, Wang CH, Lin MT, Chang CP, Lin HJ. Combined Hemorrhagic Shock and Unilateral Common Carotid Occlusion Induces Neurological Injury in Adult Male Rats. Int J Med Sci. 2017 Oct 15;14(13):1327-1334.
  • Lin HJ, Hsu CC, Chio CC, Tian YF, Lin MT, Lin TW, Chang CH, Chang CP. Gamma-Secretase Inhibitors Attenuate Neurotrauma and Neurogenic Acute Lung Injury in Rats by Rescuing the Accumulation of Hypertrophic Microglia. Cell Physiol Biochem. 2017;44(5):1726-1740.
  • Lin W, Hsuan YC, Lin MT, Kuo TW, Lin CH, Su YC, Niu KC, Chang CP, Lin HJ. Human Umbilical Cord Mesenchymal Stem Cells Preserve Adult Newborn Neurons and Reduce Neurological Injury after Cerebral Ischemia by Reducing the Number of Hypertrophic Microglia/Macrophages. Cell Transplant. 2017 Nov;26(11):1798-1810.
  • Lin W, Hsuan YC, Su YC, Lin CH, Lin MT, Chen ZH, Chang CP, Lin KC. CD34- human placenta-derived mesenchymal stem cells protect against heat stroke mortality in rats. Oncotarget. 2017 Dec 15;9(2):1992-2001.