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2026

  • Jia-Yi Hong, Chung-Ching Chio, Ching-Ping Chang, Jui-Ti Ma, Chung-Hsin Tseng,Chi-Chun Chen, Shu-Chun Kuo*. System for the automatic segmentation of retinal layers and the quantification of individual layer thicknesses and areas. Biomedical Signal Processing and Control 1 April 2026, 114: 109271.

  • Kang-Wei Tu, Chien-Cheng Huang, Mao-Tsun Lin, Ko-Chi Niu, Cheng-Hsien Lin, Pi-Yu Chao, Ching-Ping Chang*, Jimmy LianPing Mau*. Hyperbaric oxygen attenuates periodontal bone loss in a rat model of ligature-induced periodontitis. International Journal of Medical Science 2026; 23(2): 478-496.

  • Shu-Chun Kuo*, Suan Hwang, Chia-Yi Lee, Chung-Hsin Tseng, Ting-Feng Wu, Pi-Yu Chao, Wen-Pin Liu, Anthony Lu, Chao-Hung Yeh, Ching-Ping Chang*, Chung-Ching Chio*. Stem cells ameliorate neurotrauma-induced visual disturbances and retinopathy via broad normalization of the β-catenin-related signaling pathway. International Journal of Medical Science 2026; 23(3):758-779.

2025

  • Kangli Zhang‡, Xiaojing Lin‡, Ching-Ping Chang‡, Xueqing Yi, Wei Wu, Melissa J. Walker, Qingjian Ding, Kai Liu, Chuanning Sun, Yanping Sun, Zhongya Shi, Cheng-Hsien Lin**, and Gang Sun*. Heat acclimation prevents neurobehavioral and physiological disorders in mice exposed to chronic aircraft noise. Physiological Reports 2025 Oct;13(19):e70575

  • Po-Chun Wang, Wei-Ting Lin, Jun-Wei Huang, Yi-Ju Li, Tsung-Yuan Kuo, Chi-Sheng Chien*, Ching-Ping Chang, Tzer-Min Lee. Preparation of fluorapatite-containing flower-like structure coatings by micro-arc oxidation combined with ion-exchange technology. Surface & Coatings Technology 15 November 2025, 516: 132688.

  • Kun-Lin Hsieh, Kuan-Hua Huang, Ching-Ping Chang, Hung-Wen Tsai, Yu-Hao Chang, Yi-Ru Zheng, Huei-Sheng Huang *. CUB domain-containing protein 1 signaling dysregulates gemcitabine metabolism contributing to therapeutic resistance in T24 cells. PLOS ONE 2025, 20(9): e0331289. https://doi.org/10.1371/journal.pone.0331289

  • Tzu-Hao Chen, Chien-Chin Hsu, Hung-Jung Lin, Ching-Ping Chang*, Chien-Cheng Huang*, Ying-Jan Wang*. Carbon monoxide poisoning triggers intestinal injury, inflammation, and microbiota dysbiosis that drive metabolic perturbations. Life Sciences. 2025 October 1, 378: 123839. doi: 10.1016/j.lfs.2025.123839

  • Tzu-Hao Chen, Chien-Chin Hsu, Ching-Ping Chang*, Chien-Cheng Huang*, Ying-Jan Wang*. Hyperbaric oxygen therapy attenuates carbon monoxide-induced lung injury by restoring mitochondrial dynamics and suppressing Pink1/Parkin-mediated mitophagy. Environmental Pollution 2025 Sep 1;380:126521. doi: 10.1016/j.envpol.2025.126521

  • Yu-Rui Hung‡, Yu-Ling Wang‡, Shu Cing Wu, Lung-Chih Kuo, Ching-Ping Chang, and Chi-Chun Chen*. An automated MCU-based eight-arm maze for cognitive memory assessment in rats of Alzheimer's disease model. Sensors and Materials 2025. 37(7): 2909–2924.

  • Chon-Seng Hong, Nan-Chun Wu, Yu-Wen Lin, You-Cheng Lin, Jhih-Yuan Shih, Ko-Chi Niu, Mao-Tsun Lin, Ching-Ping Chang, Zhih-Cherng Chen, Wei-Chih Kan, Wei-Ting Chang. Hyperbaric oxygen therapy attenuated limb ischemia in mice with high-fat diet by restoring Sirtuin 1 and mitochondrial function. Free Radical Biology and Medicine 2025 Mar 16:230:263-272.

  • Ruei-En Hu, Chang-Chun Chang, Tzu-Hao Chen, Ching-Ping Chang, Chi-Hua Yu, I-Son Ng. De novo carbon monoxide dehydrogenase and carbonic anhydrase using molecular dynamics and deep generative model. Process Biochemistry, 2025 March, 150: 221-228.

  • Wen-Shuo Chang, Chien-Cheng Huang, Tzu-Hao Chen, Ssu-Han Chao, Cheng-Hsien Lin, Ching-Ping Chang*, Chi-Sheng Chien*. Hyperbaric oxygen potentiates platelet-rich plasma composition and accelerates bone healing. Journal of Orthopaedic Translation 2025 Jan 19; 51:1-12.

  • Sheng-Yow Ho, Chia-Hui Lin, Cheng-Hsien Lin, Mao-Tsun Lin, Jui-Ti Ma, Ying-Jan Wang, Li-Tsun Shieh*, Ching-Ping Chang*, Hung-Jung Lin *. Hyperbaric oxygen therapy improves cognitive function and hippocampal neurogenesis after brain irradiation via mitigating hippocampal microgliosis and lipid peroxidation. Int J Med Sci 2025 Jan; 22:283-297.

  • Lan-Wan Wang, Chien-Wei Hsiung, Ching-Ping Chang, Mao-Tsun Lin, Shyi-Jou Chen. Neuroserpin normalization by mesenchymal stem cell therapy after encephalopathy of prematurity in neonatal rats. Pediatric Research 2025 Feb;97(3):1199-1208. doi: 10.1038/s41390-024-03412-z

2024

  • Chien-Cheng Huang, Tzu-Hao Chen, Chung-Han Ho, Yi-Chen Chen, Wei-Ting Chang, Chien-Chin Hsu, Hung-Jung Lin, Ching-Ping Chang, How-Ran Guo. Hypothyroidism following carbon monoxide poisoning: An epidemiological study supported by animal experiments. Ecotoxicol Environ Saf. 2024 Sep 15;283:116772.

  • Cheng-Hsien Lin, Ling-Yu Tang, MS, Lin-Yu Wang*, Ching-Ping Chang. Thrombomodulin Improved Cognitive Deficits in Heat-Stressed Mice. The International Journal of Neuropsychopharmacology 2024 Jul 1;27(7):pyae027. doi: 10.1093/ijnp/pyae027

  • Wan-Yin Kuo, Chien-Cheng Huang, Chi-An Chen, Chung-Han Ho, Ling Yu Tang, Hung-Jung Lin, Shih-Bin Su, Jhi-Joung Wang, Chien-Chin Hsu*, Ching-Ping Chang*, How-Ran Guo*. Heat-related illness and dementia: a study integrating epidemiological and experimental evidence. Alzheimer’s Disease & Therapy 2024 Jul 3;16(1):145. doi: 10.1186/s13195-024-01515-7.

  • Lan-Wan Wang , Chung-Ching Chio, Chien-Ming Chao, Pi-Yu Chao, Mao-Tsun Lin, Ching-Ping Chang, Hung-Jung Lin.Mesenchymal stem cells reduce long-term cognitive deficits and attenuate myelin disintegration and microglia activation following repetitive traumatic brain injury. Science Progress 2024 Jan-Mar;107(1):368504241231154.

  • Lan-Wan Wang, Kuan-Hung Cho, Pi-Yu Chao, Li-Wei Kuo, Chia-Wen Chiang, Chien-Ming Chao, Mao-Tsun Lin, Ching-Ping Chang*, Hung-Jung Lin*, Chung-Ching Chio*. White and gray matter integrity evaluated by MRI-DTI can serve as noninvasive and reliable indicators of structural and functional alterations in chronic neurotrauma. Scientific Reports Sci Rep. 2024 Mar 27;14(1):7244.

  • Yu-Ling Wang, Chi-Chun Chen, Ching-Ping Chang. Effect of stress on the rehabilitation performance of rats with repetitive mild fluid percussion-induced traumatic brain injuries. Cognitive Neurodynamics 2024 Feb;18(1):283-297.

  • Kun-Lin Hsieh, Tzong-Bor Sun, Kuan-Hua Huang, Cheng-Hsien Lin, Ling-Yu Tang, Chien-Liang Liu*, Chien-Ming Chao*, Ching-Ping Chang*. Hyperbaric oxygen preconditioning normalizes scrotal temperature, sperm quality, testicular structure, and erectile function in adult male rats subjected to exertional heat injury. Molecular and Cellular Endocrinology 2024 Feb 8:112175.

  • Mahmoud Z. Ibrahim*, A. A. D. Sarhan*, T. Y. Kuo, Farazila Yusof, M. Hamdi*, C. P. Chang, T. M. Lee, C. S. Chien. Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility. Arabian Journal for Science and Engineering 2024; 49:10547–10559. https://doi.org/10.1007/s13369-023-08406-3.

2023

  • Mahmoud Z. Ibrahim*, A. A. D. Sarhan*, T. Y. Kuo, Farazila Yusof, M. Hamdi*, C. P. Chang, T. M. Lee, C. S. Chien. Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility. Arabian Journal for Science and Engineering (2023 Nov.).
  • Tzong-Bor Sun, Kuo-Feng Huang, Ko-Chi Niu, Cheng-Hsien Lin, Wen-Pin Liu, Chao-Hung Yeh, Shu-Chun Kuo*, Ching-Ping Chang*. Hyperbaric oxygen therapy suppresses hypoxia and reoxygenation injury to retinal pigment epithelial cells through activating peroxisome proliferator activator receptor-alpha signalling. J Cell Mol Med. 2023; 27:3189–3201.
  • Tian-Hoe Tan,Shih-Wen Li, Chih-Wei Chang, Yuan-Chih Chen, Yu-Hsuan Liu, Jui-Ti Ma, Ching-Ping Chang*, Pao-Chi Liao*. Hair biomarkers in Amyloid-β induced rat model of Alzheimer's disease using mass spectrometry-based untargeted metabolomics. Mol Neurobiol 2023 Aug; 60:4373–4395.
  • Chien-Ming Chao, Lin-Yu Wang, Chien-Cheng Huang, Wei-Ting Chang, Ling-Yu Tan, Mao-Tsun Lin, Ching-Ping Chang*. Myocardial structure and functional alterations in a preclinical model of exertional heat stroke. Life Sciences 2023 March 31; 323:121640.
  • Chien-Liang Liu, Hung-Wen Tsai, Shu-Ling Peng, Ching-Ping Chang, Yi-Hui Ho, Meng-Chien Lu, Yu-Hao Chang, Hoi-Lam Tam, Huei-Sheng Huang. CDCP1 (CUB domain-containing protein 1) is a potential urine-based biomarker in the diagnosis of low-grade urothelial carcinoma. PLos One 2023 Mar 2; 18(3): e0281873.
  • Gang Sun, Cheng-Hsien Lin, Guiping Mei, Jia Gu, Sheng-Fang Fan, Xiaohong Liu, Ruoxu Liu, Xun-Wei Liu, Xiao-Sen Chen, Cheng Zhou, Xueqing Yi, Peng Jin, Ching-Ping Chang*, Xiao-Jing Lin*. Recovery of neurosurgical high-frequency electroporation injury in the canine brain can be accelerated by 7,8-dihydroxyflavone. Biomed Pharmacother. 2023 February 9; 160: 114372.

2022

  • Kuan-Ting Chen, Jun-Wei Huang,Wei-Ting Lin,Tsung-Yuan Kuo,Chi-Sheng Chien*, Ching-Ping Chang, Yung-Ding Lin. Effects of micro-arc oxidation discharge parameters on formation and biomedical properties of hydroxyapatite-containing flower-like structure coatings. Materials 2022 December 21;16(1):57.
  • Lan-Wan Wang, Hung-Jung Lin, Chien-Ming Chao, Mao-Tsun Lin, Lin-Yu Wang, Lan-Hsiang Chein, Ching-Ping Chang*, Chung-Ching Chio*. The interrelationships between neuronal viability, synaptic integrity, microglial responses, and amyloid-beta formation in an in vitro neurotrauma model. Sci Rep. 2022 Dec 20;12(1):22028.
  • Kuan-Hua Huang, Ching-Ping Chang, Lan-Hsiang Chien, Chien-Feng Li, Yu-Yi Chan, and Ting-Feng Wu. Uncovering the inhibitory molecular mechanism of pomegranate peel to urinary bladder urothelial carcinoma using proteomics techniques. Life (Basel). 2022 Nov 9; 12(11): 1839.
  • Chien-Cheng Huang, Tzu-Hao Chen, Chung-Han Ho, Yi-Chen Chen, Rong-Jane Chen, Ying-Jan Wang, Chien-Chin Hsu, Hung-Jung Lin, Jhi-Joung Wang, Ching-Ping Chang, How-Ran Guo. Risks of developing diabetes and hyperglycemic crisis following carbon monoxide poisoning: A study incorporating epidemiologic and animal results. Clinical Epidemiology 2022 November, 2022(14): 1265–1279.
  • Chi-Chun Chen, Yu-Ling Wang*, Ching-Ping Chang. Optimized ladder-climbing rehabilitation training for various stroke severity levels in rats. IET Circuits, Devices & Systems 2022 November. 16(8): 598-610.
  • Wei-Ting Lin, Z.W. Lin, Tsung-Yuan Kuo, Chi-Sheng Chien*, J.W. Huang, Y.L. Chung, Ching-Ping Chang, M.Z. Ibrahim, Hwa-Teng Lee. Mechanical and biological properties of atmospheric plasma-sprayed carbon nanotube-reinforced tantalum pentoxide composite coatings on Ti6Al4V alloy. Surface & Coatings Technology May 15 2022, 437:128356.
  • Yu-Ling Wang, Chung-Ching Chio, Shu-Chun Kuo, Chao-Hung Yeh, Jui-Ti Ma, Wen-Pin Liu, Mao-Tsun Lin, Kao-Chang Lin, Ching-Ping Chang*. Exercise rehabilitation and/or astragaloside attenuate amyloid-beta pathology by reversing BDNF/TrkB signaling deficits and mitochondrial dysfunction. Molecular Neurobiology 2022 May;59(5):3091-3109.