學術研究 - 奇美醫學中心腦創傷中心

本科於教學方面，不遺餘力。對於住院醫師、實習醫師、見習醫師分別訂立不同教學計劃，因材施教。每月都有常規性病例討論、雜誌期刊選讀。

時　間		主　題	地　點
雙月第2個	週四	腦創傷中心團隊會議	八樓空橋討論室
每月第2, 4	週五	實習醫學生Traumatic brain injury journal reading	6A討論室
不定期	週五	實驗室進度報告	研究大樓討論室

研究發表

2025

作者姓名(順位)	論文題目/發表雜誌名稱
Xiao-Han Vivian Yap, Kuan-Chi Tu, Nai-Ching Chen, Che-Chuan Wang, Chia-Jung Chen , Chung-Feng Liu, Tee-Tau Eric Nya , Ching-Lung Kuo.	Developing a high-performance AI model for spontaneous intracerebral hemorrhage mortality prediction using machine learning in ICU settings. BMC Med Inform Decis Mak. 2025 Mar 28;25(1):149.
Tee-Tau Eric Nyam, Kuan-Chi Tu, Yun-Hsuan Kuo, Che-Chuan Wang, Chung-Feng Liu, Jen-Chieh Liao, Ching-Lung Kuo	Age and pupil size: key predictors of mortality in traumatic brain injury patients with GCS 3. Front Neurol . 2025 Apr 4:16:1536421.
Kuan-Chi Tu, Yung-De Kuo, Tee-Tau Eric Nyam, Yu-Shan Ma , Mei-I Sung, Chung-Feng Liu, Ching-Lung Kuo	Predicting emergency mortality risk in traumatic brain injury: comparative analysis of machine learning and large language model GPT-5 .Int J Med Inform. 2026 Apr 1:209:106268..
Bei-Yi Su, Tee-Tau Eric Nyam, Che-Chuan Wang, Hsin-Fan Wang, Jinn-Rung Kuo	Influence of Pre-existing Diabetes Mellitus on Executive Function Deficits in Adult Traumatic Brain Injury. World Neurosurg . 2025 Jul:199:123999.
Nai-Wen Guo, Willy Chou, Jinn-Rung Kuo, Yu-Chi Liao, Ming-Tsung Chuang, Bei-Yi Su	The executive functions among patients with an initial Glasgow coma scale score of 15. Appl Neuropsychol Adult. 2025 Sep-Oct;32(5):1317-1325.

2024

作者姓名(順位)	論文題目/發表雜誌名稱
Tee-Tau Eric Nyam, Hsiao-Yue Wee, Min-Hsi Chiu, Kuan-Chi Tu, Che-Chuan Wang, Yao-Tsung Yeh, Ching-Lung Kuo.	Hyperbaric Oxygen Therapy Reduces the Traumatic Brain Injury-Mediated Neuroinflammation Through Enrichment of Prevotella Copri in the Gut of Male Rats.Neurocrit Care. 2024 Dec;41(3):798-812.
Tee-Tau Eric Nyam, Kuan-Chi Tu, Nai-Ching Chen, Che-Chuan Wang, Chung-Feng Liu, Ching-Lung Kuo, Jen-Chieh Liao	Predictive Modeling of Long-Term Care Needs in Traumatic Brain Injury Patients Using Machine Learning.Diagnostics (Basel). 2024 Dec 25;15(1):20.
Yun-Hsuan Kuo , Jinn-Rung Kuo, Tee-Tau Eric Nyam, Che-Chuan Wang, Bei-Yi Su	Beyond brain injury: Examining the neuropsychological and psychosocial sequelae of post-traumatic epilepsy.J Int Neuropsychol Soc . 2024 Oct;30(8):777-784.
Jinn-Rung Kuo, Yuh-Ming Chang, Yen-Min Huang, Yun-Chen Chang, Chih-Chien Lee, Li-Sung Hsu, Tsung-Hsi Yang	Taxifolin Inhibits the Proliferation of Glioblastoma Multiforme Cells via Apoptosis and Autophagy.Current Topics in Nutraceutical Research 22(1):366-372

2023

作者姓名(順位)	論文題目/發表雜誌名稱
Eric Nyam TT, Wee HY, Chiu MH, Tu KC, Wang CC, Yeh YT, Kuo CL.	Hyperbaric oxygen therapy reduces the traumatic brain injury-mediated neuroinflammation through enrichment of Prevotella copri in the gut of male rats. Neurocritical Care. 2023, 11. DOI: https://doi.org/10.21203/rs.3.rs-3511955/v1
Chen YT, Nyam TT, Tsai LC, Chang CH, Su CL, Ho CH, Chio CC, Gean PW, Kuo JR.	Pretreatment with Lovastatin Improves Depression-Like Behavior After Traumatic Brain Injury Through Activation of the AMPK Pathway. World Neurosurg. 2023 Dec;180:e350-e363.
Guo NW, Chou W, Kuo JR, Liao YC, Chuang MT, Su BY.	The executive functions among patients with an initial Glasgow coma scale score of 15. Appl Neuropsychol Adult. 2023 Oct 25:1-9.
Tu KC, Eric Nyam TT , Chen NC, Chang MC, Yu TC, Wang CC, Liu CF, Kuo CL.	Machine Learning Algorithm Predicts Mortality Risk in Intensive Care Unit for Patients with Traumatic Brain Injury. Diagnostics (Basel). 2023 Sep 21;13(18):3016.
Kuo JR, Su BY.	Neuropsychological Impairments in Patients With Post-traumatic Epilepsy: A Scoping Review. World Neurosurg. 2023 Aug;176:85-97.
6. Chen HT, Hung KC, Hsu YC, Kuo JR, Chang YJ, Chen IW, Sun CK.	Efficacy of acupuncture for pain relief in patients receiving extracorporeal shock wave lithotripsy: a meta-analysis of randomized controlled studies. Front Med (Lausanne). 2023 Jun 2;10:1114485.

2022

作者姓名(順位)	論文題目/發表雜誌名稱
Hung KC, Chen HT, Hsing CH, Kuo JR, Ho CN, Lin YT, Chang YJ, Chiu SF, Sun CK.	Impact of prior bariatric surgery on risk and severity of COVID-19 infection: A meta-analysis of observational studies. Obes Res Clin Pract. 2022 Nov;16(6):439-446.
Wu TC, Weng JY, Lin CJ, Tsui YK, Kuo JR, Chen PJ, Wang JJ.	Patient-Specific 3D-Print Extracranial Vascular Simulators and Infrared Imaging Platform for Diagnostic Cerebral Angiography Training. Healthcare (Basel). 2022 Nov 14;10(11):2277.
Yang KS, Chen CW, Yau RB, Liang HC, Ko CC, Kuo JR, Chio CC, Lim SW.	A novel surgical technique in transforaminal lumbar interbody fusion by the bone graft delivery device: evaluation of therapeutic effect in patients with minimally invasive spine surgery. BMC Surg. 2022 Oct 26;22(1):366.
Hung KC, Huang YT, Kuo JR, Hsu CW, Yew M, Chen JY, Lin MC, Chen IW, Sun CK.	Elevated Surgical Pleth Index at the End of Surgery Is Associated with Postoperative Moderate-to-Severe Pain: A Systematic Review and Meta-Analysis. Diagnostics (Basel). 2022 Sep 6;12(9):2167.
Tu KC, Eric Nyam TT, Wang CC, Chen NC, Chen KT, Chen CJ, Liu CF, Kuo JR.	A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage. Brain Sci. 2022 May 7;12(5):612.
Lu CC, Nyam TE, Ho CH, Kuo JR, Chio CC, Wang JJ, Wang CC.	New diagnosis of cancer in mild and moderate/severe traumatic brain injury patients in a 12-year population-based study. BMC Cancer. 2022 Mar ;22(1):291.

2021

作者姓名(順位)	論文題目/發表雜誌名稱
Hung YC, Kuo YH, Hsieh PW, Hsieh TY, Kuo JR, Wang SJ.	Chlorogenic Acid Decreases Glutamate Release from Rat Cortical Nerve Terminals by P/Q-Type Ca2+ Channel Suppression: A Possible Neuroprotective Mechanism.Int J Mol Sci. 2021 Oct 23;22(21):11447.
Lim SW, Su HC, Nyam TE, Chio CC, Kuo JR, Wang CC.	Ceftriaxone therapy attenuates brain trauma in rats by affecting glutamate transporters and neuroinflammation and not by its antibacterial effects. BMC Neurosci. 2021 Sep 14;22(1):54.
Kuo JR	奇美醫學中心創傷性腦損傷疾病認證經驗分享。Journal of healthcare quality 2021.sep. ;15(5) p 80-83
Wang CC, Hsieh PW, Kuo JR, Wang SJ.	Rosmarinic Acid, a Bioactive Phenolic Compound, Inhibits Glutamate Release from Rat Cerebrocortical Synaptosomes through GABAA Receptor Activation. Biomolecules. 2021 Jul 15;11(7):1029.
Lu CC, Nyam TE, Kuo JR, Lee YL, Chio CC, Wang CC.	The neuroprotective effects of AMN082 on neuronal apoptosis in rats after traumatic brain injury. BMC Neurosci. 2021 Jun 25;22(1):44.
Huang YK, Lin CK, Wang CC, Kuo JR, Lai CF, Chen CW, Lin BS.	A novel wireless optical technique for quantitative evaluation of cerebral perfusion pressure in a fluid percussion animal model of traumatic brain injury. Quant Imaging Med Surg. 2021 Jun;11(6):2388-2396.
Wang CC, Kuo JR, Wang SJ.	Fingolimod inhibits glutamate release through activation of S1P1 receptors and the G protein βγ subunit-dependent pathway in rat cerebrocortical nerve terminals. Neuropharmacology. 2021 Mar 1;185:108451

2020

作者姓名(順位)	論文題目/發表雜誌名稱
Lee YL,Lim SW,Zheng HX,Chang WT,Nyam TE,Chio CC, Kuo JR,Wang CC.	The Short-Term Effects of Isolated Traumatic Brain Injury on the Heart in Experimental Healthy Rats. Neurocrit Care2020 Oct;33(2):438-448.
Chong AJ, Wee HY, Chang CH, Chio CC, Kuo JR, Lim SW.	Effects of a High-Fat Diet on Neuroinflammation and Apoptosis in Acute Stage After Moderate Traumatic Brain Injury in Rats. Neurocrit Care. 2020 Aug;33(1):230-240.
Kuo JR, Lim SW, Zheng HX, Ho CH, Chang CH, Chio CC, Wee HY.	Triglyceride is a Good Biomarker of Increased Injury Severity on a High Fat Diet Rat After Traumatic Brain Injury. Neurochem Res. 2020 Jul;45(7):1536-1550.
Zheng HX, Eric Nyam TT, Liu CA, Lee YL, Kuo JR, Sung KC.	Spontaneous Spinal Epidural Hematoma After Normal Spontaneous Delivery with Epidural Analgesia: Case Report and Literature Review. World Neurosurg. 2020 May;137:214-217.
Wang CC, Ho YH, Hung CF, Kuo JR, Wang SJ.	Xanthohumol, an active constituent from hope, affords protection against kainic acid-induced excitotoxicity in rats. Neurochem Int. 2020 Feb;133:104629.

2019

作者姓名(順位)	論文題目/發表雜誌名稱
Chong AJ,Lim SW,Lee YL,Chio CC,Chang CH, Kuo JR,Wang CC.	The Neuroprotective Effects of Simvastatin on High Cholesterol Following Traumatic Brain Injury in Rats.World Neurosurg. 2019 Dec;132:e99-e108.
Chong AJ,Wee HY,Chang CH,Chio CC,Kuo JR, Lim SW.	Effects of a High-Fat Diet on Neuroinflammation and Apoptosis in Acute Stage After Moderate Traumatic Brain Injury in Rats.Neurocrit Care. 2019 Dec 11.
Eric Nyam TT,Lim SW,Ho CH,Liao JC,Wang JJ,Chio CC,Kuo JR,Wang CC	In-Hospital Mortality After Spinal Surgery in Hemodialysis Patients: An 11-Year Population-Based Study.World Neurosurgery Volume 122, 2019 February;Pages e667-e675.
Eric Nyam TT, Ho CH, Chio CC, Lim SW, Wang JJ, Chang CH, Kuo JR, Wang CC.	Traumatic Brain Injury Increases the Risk of Major Adverse Cardiovascular and Cerebrovascular Events: A 13-Year, Population-Based Study.World Neurosurg. 2019 Feb;122:e740-e753.
Wee HY, Ho CH, Chang CH, Chio CC, Wang JJ, Wang CC, Kuo JR.	Probability of New-Onset Cancer Between Patients with Traumatic Brain Injury and a Comparison General Population Cohort.World Neurosurg. 2019 Jan;121:e817-e826.

2018

作者姓名(順位)	論文題目/發表雜誌名稱
Tseng WH, Tian YF, Liao AC, Chen MJ, Ho HY, Kuo JR, Huang SK.	Successful reuse of a transplanted kidney 9 years after initial transplantation: 4-year follow-up. BMC Nephrol. 2018 Sep 17;19(1):234.
Sun DP, Lee LH, Tian YF, Zheng HX, Kuo JR, Wang CC.	How to Deal with the Empty Space After Organ Removal for Transplantation: A Single Medical Center Experience.World Neurosurg. 2018 Jul;115:e299-e304.
Lee YL, Kuo JR	Intraparenchymal Hemorrhage after Burr Hole Drainage: A Case Report and Review of Literature.Open Journal of Clinical and Medical Case 2018 Vol 4:Issue5:1384
Chen PJ, Weng JY, Kuo JR	Combined computer-aided and 3D printing technology for pre-operative planning in spine fracture surgery.2018 IEEE International Conference on Applied System Invention (ICASI) April 2018 P 793-796
Kuo JR	Neurogenic Stress Cardiomyopathy.Stress (Takotsubo) Cardiomyopathy P 81-102
Eric Nyam TT, Ho CH, Wang YL, Lim SW, Wang JJ, Chio CC, Kuo JR, Wang CC.	The Risk of Traumatic Brain Injury Occurring among Patients with Parkinson'sDisease: A 14-Year Population-Based Study. World Neurosurg. 2018 Feb 13.
Wang CC, Wee HY, Hu CY, Chio CC, Kuo JR.	The Effects of Memantine on Glutamic Receptor-Associated Nitrosative Stress in a Traumatic Brain Injury Rat Model. World Neurosurg. 2018 Jan 31.
Wang CC, Kuo JR, Huang SK, Wang SJ.	Metabotropic glutamate 7 receptor agonist AMN082 inhibits glutamate release in rat cerebral cortex nerve terminal. Eur J Pharmacol. 2018 Mar 15;823:11-18.
Lim SW, Nyam Tt E, Hu CY, Chio CC, Wang CC, Kuo JR.	Estrogen Receptor-α is Involved in Tamoxifen Neuroprotective Effects in a Traumatic Brain Injury Male Rat Model. World Neurosurg. 2018 Jan 31.
Ho CH, Liang FW, Wang JJ, Chio CC, Kuo JR.	Impact of grouping complications on mortality in traumatic brain injury: A nationwide population-based study. PLoS One. 2018 Jan 11;13(1):e0190683.

2017

作者姓名(順位)	論文題目/發表雜誌名稱
Weng JY, Wang CC, Chen PJ, Lim SW, *Kuo JR.	The Application of a three-dimensional printed product to fill the space after organ removal. World Neurosurg. 2017 Nov;107:1045.e17-1045.e19
Lim SW, Eric Nyam TT, Ho CH, Shiue YL, Wang JJ, Chio CC, *Kuo JR.	Increased Risk of Anxiety or Depression After Traumatic Spinal Cord Injury in Patients with Preexisting Hyperlipidemia: A Population-Based Study. World Neurosurg. 2017 Oct;106:402-408...
Ao KH, Ho CH, Wang CC, Wang JJ, Chio CC, *Kuo JR.	The increased risk of stroke in early insomnia following traumatic brain injury: a population-based cohort study. Sleep Med. 2017 Sep;37:187-192.
Yu SC, Kuo JR, Shiue YL, Yu ZX, Ho CH, Wu CC, Wang JJ, Chu CC, Lim SW.	One-Year Mortality of Patients with Chronic Kidney Disease After Spinal Cord Injury: A 14-Year Population-Based Study. World Neurosurg. 2017 Sep;105:462-469.
Lim SW, Ao KH, Ho CH, Tseng CJ, Wang JJ, Chio CC, *Kuo JR.	The Association Between Ventriculo-Peritoneal Shunt and Acute Appendicitis in Patients with Traumatic Brain Injury: A 14-Year, Population-Based Study. World Neurosurg. 2017 Jul;103:106-113.
Chang CY, Hung CF, Huang SK, Kuo JR, Wang SJ.	Amiodarone reduces depolarization-evoked glutamate release from hippocampual synaptosomes. J Pharmacol Sci. 2017 Mar;133(3):168-175.
Lim SW, Sung KC, Shiue YL, Wang CC, Chio CC, *Kuo JR.	Hyperbaric Oxygen Effects on Depression-Like Behavior and Neuroinflammation in Traumatic Brain Injury Rats. World Neurosurg. 2017 Apr;100:128-137.
Nyam TE, Ao KH, Hung SY, Shen ML, Yu TC, *Kuo JR.	FOUR Score Predicts Early Outcome in Patients After Traumatic Brain Injury. Neurocrit Care. 2017 Apr;26(2):225-231.
Lim SW, Shiue YL, Liao JC, Wee HY, Wang CC, Chio CC, Chang CH, Hu CY, *Kuo JR.	Simvastatin Therapy in the Acute Stage of Traumatic Brain Injury Attenuates Brain Trauma-Induced Depression-Like Behavior in Rats by Reducing Neuroinflammation in the Hippocampus. Neurocrit Care. 2017 Feb;26(1):122-132.
Lim SW, Shiue YL, Ho CH, Yu SC, Kao PH, Wang JJ, *Kuo JR.	Anxiety and Depression in Patients with Traumatic Spinal Cord Injury: A Nationwide Population-Based Cohort Study. PLoS One. 2017 Jan 12;12(1):e0169623.

2016

作者姓名(順位)	論文題目/發表雜誌名稱
Liao JC,Ho CH,Chiu HY,Wang YL,Kuo LC,Liu C,Wang JJ,Lim SW,Kuo JR.	Physiotherapists working in clinics have increased risk for new-onset spine disorders - A 12-year population-based study. Medicine.2016 Aug;95(32):e4405 (SCI: 1.206, rank 77/151=50.9% )
Lim SW,Shiue YL,Liao JC,Wee HY,Wang CC,Chio CC,Chang CH,Hu CY,Kuo JR.	Simvastatin Therapy in the Acute Stage of Traumatic Brain Injury Attenuates Brain Trauma-Induced Depression-Like Behavior in Rats by Reducing Neuroinflammation in the Hippocampus. Neurocrit Care. 2016 Jul 12. (SCI: I.F 2.488, rank 87/192=45.3%)
Wee HY,Ho CH,Liang FW,Hsieh KY,Wang CC,Wang JJ,Chio CC,Chang CH,Kuo JR.	Increased risk of new-onset depression in patients with traumatic brain injury and hyperlipidemia: the important role of statin medications. J Clin Psychiatry. 2016 Apr;77(4):505-11. (SCI: I.F 5.408, rank 18/140=12.8%)
Wang CC,Kuo JR,Chen YC,Chio CC,Wang JJ,Lin BS.	Brain tissue oxygen evaluation by wireless near-infrared spectroscopy. J Surg Res. 2016 Feb;200(2):669-75. (SCI: I.F 2.198, rank 60/199=30.1%)
Wang CC,Wee HY,Chio CC,Hu CY,Kuo JR	Effects of tamoxifen on traumatic brain injury-induced depression in male rats. Formosan Journal of Surgery (2016) 49, 101-109.

2015

作者姓名(順位)	論文題目/發表雜誌名稱
Cheng CY,Ho CH,Wang CC,Liang FW,Wang JJ,Chio CC,Chang CH,Kuo JR	One-Year Mortality after Traumatic Brain Injury in Liver Cirrhosis Patients--A Ten-Year Population-Based Study. Medicine (Baltimore). 2015 Oct;94(40):e1468. doi: 10.1097/MD.0000000000001468.
Wee HY,Wang CC,Kuo JR	Vascular injury after lumbar discectomy mimicking appendicitis: Report of a case. Asian J Neurosurg. 2015 Jul – Sep ;10 (3) :243-5.
Wee HY,Lim SW,Chio CC,Niu KC,Wang CC,Kuo JR	Hyperbaric oxygen effects on neuronal apoptosis associations in a traumatic brain injury rat model. J Surg Res.2015 Aug ; 197(2):382-9. doi: 10.1016/j.jss.2015.04.052. Epub 2015 Apr 21.

2014

作者姓名(順位)	論文題目/發表雜誌名稱
Kuo JR,Lin SS,Liu J,Chen SH,Chio CC,Wang JJ,Liu JM.	Deep brain light stimulation effects on glutamate and dopamine concentration.Biomed Opt Express. 2014 Dec 3;6(1):23-31. doi: 10.1364/BOE.6.000023. eCollection 2015.
Ho CH,Hsieh KY,Liang FW,Li CJ,Wang JJ,Chio CC,Chang CH,Kuo JR .	Pre-existing Hyperlipidaemia Increased the Risk of New-onset Anxiety Disorders After Traumatic Brain Injury: A 14-year Population-based Study.BMJ Open. 2014 Jul 17;4(7):e005269. doi: 10.1136/bmjopen-2014-005269.
Liao JC,Ho CH,Liang FW,Wang JJ,Lin KC,Chio CC,Kuo JR.	One-year mortality associations in hemodialysis patients after traumatic brain injury – An eight-year population-based study. Plos one 2014 Apr 8;9(4):e93956. doi: 10.1371/journal.pone.0093956. eCollection 2014. IF: 3.73, R/C=7/56 (Multidisciplinary Science)
Tsai YT,Wang CC,Leung PO,Lin KC,Chio CC,Hu CY,Kuo JR.	Extracellular signal-regulated kinase 1/2 is involved in a tamoxifen neuroprotective effect in a lateral fluid percussion injury rat model. J Surg Res. 2014 Feb 15. pii: S0022-4804(14)00153-X IF: 2.018, R/C=56/198 (Surgery)
Kuo JR,Lin BS,Cheng CL,Chio CC.	Hypoxic-state estimation of brain cells by using wireless near-infrared spectroscopy.IEEE J Biomed Health Inform. 2014 Jan;18(1):167-73. doi: 10.1109/JBHI.2013.2261310.
Wang CC,Lin KC,Lin BS,Chio CC,Lin SF,Kuo JR.	The effects of brain temperature changes on intracranial pressure cerebral perfusion pressure and prognosis after traumatic brain injury.南台學報 38卷第3期9月 11-20 (Non-SCI)
Wee HY,Kuo JR.	Never neglect the atmospheric pressure effect on a brain with a skull defect. International Medical Case Reports Journal 2014:7 1–3 (non-SCI)

2013

作者姓名(順位)	論文題目/發表雜誌名稱
Wang CC,Chen YS,Lin BS,Chio CC,Hu CY,Kuo JR.	The neuronal protective effects of local brain cooling at the craniectomy site after lateral fluid percussion injury in a rat model. J Surg Res. 2013 Dec;185(2):753-62 IF: 2.018, R/C=56/198 (Surgery)
Lim SW,Wang CC,Wang YH,Chio CC,Niu KC,Kuo JR.	Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with hyperbaric oxygen therapy. J Surg Res. 2013 May 21. doi:pii: S0022-4804(13)00442-3. IF: 2.247, R/C=51/199 (Surgery)
Wang CC,Lin KC, Lin BS,Chio CC,Kuo JR.	Resuscitation from experimental traumatic brain injury by magnolol therapy. J Surg Res. 2013 May 17. doi:pii: S0022-4804(13)00432-0. IF: 2.247, R/C=51/199 (Surgery)
Kuo JR,Lin BS,Cheng CL,Chio CC	Hypoxic-state estimation of brain cells by using wireless near-infrared spectroscopy. IEEE Journal of Biomedical and Health Informatics, 2013, in press. IF: 1.676 R/C=27/135 (Computer Science, Information System)
Kuo JR,Cheng YH,Chen YS,Chio CC,Gean PW	Involvement of extracellular signal regulated kinases (ERK1/2) in traumatic brain injury-induced depression in rodents. J Neurotrauma. 2013 Jan 29. [Epub ahead of print. IF: 3.64; R/C=38/192 (Clinical Neurology)
Kuo JR,Chang MH,Wang CC,Chio CC,Wang JJ,Lin BS	Wireless near-infrared spectroscopy system for determining brain hemoglobin levels in laboratory animals. J Neurosci Methods. 2013 Apr 15; 214(2):204-9. IF: 1.98; R/C= 48/72 (Biochemical research methods)
Lin KH,Kuo JR,Lu WJ,Chung CL,Chou DS,Huang SY,Lee HC,Sheu JR	Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo. Biochem Pharmacol. 2013 May 15; 85(10):1478-85. IF: 4.705; R/C= 28/261 (Pharmacology and Pharmacy)

2012

作者姓名(順位)	論文題目/發表雜誌名稱
Kuo JR,Chio CC	Brain temperature management in traumatic brain injury Fomorsan journal of Surgery 2012; 45(6): 1-5 (Noon-SCI)
Chang HY,Kuo JR,Sung KC,Liao JC,Huang SH	Repeated syncope in a needle man. Acta Neurol Taiwan. 2012 Sep; 21(3):145-6 (Non-SCI)
Chuang TJ,Lin KC,Chio CC,Wang CC,Chang CP,Kuo JR	Effects of secretome obtained from normoxia-preconditioned human enchymal stem cells in traumatic brain injury rats.J Trauma Acute Care Surg. 2012 Nov; 73(5):1161-7 (2.478; 4/24) IF: 2.478；R/C=4/24，(Emergency Medicine)
Lin KC,Niu KC,Tsai KJ,Kuo JR,Wang LC,Chio CC,Chang CP	Attenuating inflammation but stimulating both angiogenesis and neurogenesis using hyperbaric oxygen in rats with traumatic brain injury.J Trauma Acute Care Surg. 2012 Mar; 72(3):650-9. (2.478; 4/24) IF: 2.478；R/C=4/24，(Emergency Medicine)
Hsiao YH,Kuo JR,Chen SH,Gean PW	Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model. Neurobiol Dis. 2012 Mar; 45(3):1111-20. (5.403; 34/244)IF: 5.403；R/C=34/244，(Neuroscience)
Kuo JR,Wang CC,Huang SK,Wang SJ	Tamoxifen depresses glutamate release through inhibition of voltage-dependent Ca2+ entry and protein kinase Ca in rat cerebral cortex nerve terminals Neurochemistry Internal 2012; 60(2):105-14. (2.857; 116/244)IF: 2.857；R/C=116/244，(Neuroscience)
林高章,李歡芳,郭進榮,王志中	暴露於神經毒物的台灣老年人其記憶缺失及記憶抱怨的評估

2011

作者姓名(順位)	論文題目/發表雜誌名稱
Hung MH,Kuo JR,Wang CC	Chemosis: traumatic carotid cavernous fistula.ANZ J Surg. 2011 Jun; 81(6):486-7. (1.248; 110/199)IF: 1.248；R/C=110/199，(Surgery)
Cheng HT,Wang CC,Chio CC,Kuo JR.	Sphenoid ridge meningioma presenting as ischemia stroke.ANZ J Surg. 2011 Oct; 81(10):751-2. (1.248; 110/199)IF: 1.248；R/C=110/199，(Surgery)
Kuo JR,Lo CJ,Chang CP,Lin MT,Chio CC	Agmatine-promoted angiogenesis, neurogenesis, and inhibition of gliosis-reduced traumatic brain injury in rats Joural of Trauma 2011; 71:E87-93. (2.478, 4/24)IF: 2.478；R/C=4/24，(Emergency Medicine)
Kuo JR,Lo CJ,Chang CP,Lin MT,Chio CC	Attenuation of brain nitrostative and oxidative damage by brain cooling during experimental traumatic brain injury.J Biomed Biotechnol. 2011; 2011:145214. (2.436; 65/158)IF: 2.813；R/C=34/74，(Biophysics)
Kuo JR,Lo CJ,Chang CP,Lin MT,Chio CC	Prognostic predictors of outcome in an operative series in traumatic brain injury patients.Journal of Formosan medical association 2011; 110(4):258–264. (1.132; 78/155)國科會加權指數4
Kuo, JR,Lo CJ,Lu, CL,Wang CC,Lin KC.Chiao-Fang Chen	Measuring brain temperature while maintaining brain normothermia in patients with severe brain injury.Journal of Clinical Neuroscience, 2011; (18);1059-1063. (1.247; 147/192)IF: 1.247; R/C=147/192 (Clinical Neurology)
Wang JC,Huan SK,Kuo JR,Lu CL,Lin H,Shen KH	Multivariable Logistic Regressive Equation to Screen for Prostate Cancer Journal of Formosan medical association 2011; 110(11):695-700. (1.132; 78/155)國科會加權指數4
Chen CH,Kuo JR,Uen YH,Sun DP	Liver Abscess Secondary to Fish Bone Migration from the duodenum ANZ Journal of Surgery 2011 Mar; 81(3):206. (1.248; 110/199)IF: 1.248；R/C=110/199，(Surgery)

2010

作者姓名(順位)	論文題目/發表雜誌名稱
Kuo JR,Lo CJ,Chang CP,Lin MT,Chio CC	Brain cooling- stimulated angiogenesis and neurogenesis attenuated traumatic brain injury in rats.J Trauma 2010; 69:1467-1472. (2.478. 4/24)IF: 2.478；R/C=4/24，(Emergency Medicine)
Kuo JR,Wang CC,Lee HF,Chio CC,Lin KC	Hematoma density and Glasgow coma scale are independent predictors to outcomes in unilateral chronic subdural hematoma Taiwan Crit. Care Med.2010; 11:90-97 (Non-SCI)
Chio CC,Lin JW,Chang MW,Wang CC,Kuo JR,Chang CP	Therapeutic evaluation of etantercept in a model of traumatic brain injury Journal of Neurochemistry 2010; 115:921-929. (4.061; 59/244)IF: 4.061；R/C=59/244，(Neuroscience)
Wang CC,Chio CC,Chang CH,Kuo JR,Chang CP	Beneficial effect of agmatine on brain apoptosis, astrogliosis, and edema after rat transient cerebral ischemia BMC Pharmacology 2010, 10:11 (Non-SCI)
Wu SJ,Kuo JR,Chin LS	Clinical Experience of the Woodward Procedure in Sprengel’s Deformity , Formos J Surg 2010; 43:81-86 (Non-SCI)
Hung MH,Kuo JR,Huang KF,Wang WC	Sacral herpes zoster presenting as sciatica CMAJ 2010. DOI:10.1503/cmaj.091534. (8.217; 8/155)IF: 8.217; R/C=8/155, (Medicine, General and Internal)
Huang YC,Wang CC,Chio CC,Kuo JR	A Growing Pre-existing Juxta-facet Cyst after Lumbar Laminectomy : Report of a Case Formos J Surg 2010; 43:181-185 (Correspondence, Non-SCI)
Wang CC,Chio CC,Tseng CJ,Kuo JR	Distal anterior cerebral artery aneurysm: an infrequent cause of transient Ischemic attack followed by diffuse subarachnoid hemorrhage Formos J Surg (accept, 2010, Non-SCI)
Cheng CY,Wang CC,Chen TY,Kuo JR	Intracranial hypotension concurrent presented with pseudo-subarachnoid hemorrhage and tramsverse sinus thrombosis –a case report Journal of Taiwan emergency medicine (accept 2010,Non-SCI)
Hsieh YK,Chio CC,Wang CC,Li CF,Kuo JR	Trauma-related True Aneurysm of the Superficial Temporal Artery: Report of a Case Formos J Surg 2010; 43:95-98 ( Non-SCI)
Wu NC,Kuo JR,Cheng BC	Successful Treatment of a Potentially Fatal Complication of Tracheoinnominate Artery Fistula with Extracorporeal Life Support: Report of a Case Thorac Med 2010; 25: 184-189 (Non-SCI)
Liu CL,Kuo JR,Sheng KH,Wang SY,Li CF,Lee YH,Liao AC	Simultaneous Penile Gangrene and Testicular Infarction Secondary to Calciphylaxis in a Uremic Patient Urol Sci 2010; 21(2):99−102 (Non-SCI)
Tseng CJ,Kuo JR,Uen YH	Brunner’s Gland Hamartoma of the Duodenum Presenting with Intussusception: Report of a Case Formos J Surg 2010;43:91-94 (Non-SCI)

2009

作者姓名(順位)	論文題目/發表雜誌名稱
Wang CC,Chang CH,Lin HJ,Lin KC,Kuo JR	Misdiagnosis of spontaneous cervical epidural haemorrhage Eur Spine J , 2009 Jul;18 Suppl 2:210-2 IF: 2.524; R/C=23/65 (Orthopedics)
Lin KC,Wang CC,Liao YC,Kuo JR	Reactivation of herpes zoster along the trigeminal nerve with intractable pain after facial trauma: a case report and literature review BMJ case report s 2009[ doi:10.1136/bcr.07.2008.0525] ( Non-SCI)
Lin KC,Kuo JR	The difference of osmotic effects between intract and disrupted blood brain barrier. JNNP (8 April 2009)- electronic letter (4.764;4/199)IF: 4.953; R/C=4/199 (Surgery)
Hung MH,Kuo JR,Huang YC,Sun DP	Solid Pseudopapillary Tumor of the Pancreas: Images for Surgeons Formos J Surg 2009; 42:350-353 (Non-SCI)
Su YC,Kuo JR,Tsai YF,Fong Y	Solitary primary chest wall lymphoma- report of a case Thorac Med 2009; 24:346-351 (Non-SCI)

2008

作者姓名(順位)	論文題目/發表雜誌名稱
Lin KC,Kuo JR	Variability of brain death determination guidelines in leading US neurologic institutions Neurology (14 February 2008) – correspondence for Greer et al IF: 7.643; R/C=7/192 (Clinical Neurology)
Kuo JR,Chio CC,Wang CC,Chu YH,Chuang SS,Lin KC	Radiation-induced intra- and extra-cranial high-grade myxofibrosarcoma with tumor bleeding Journal of Clinical Neuroscience 2008;15: 1151–1154 IF: 1.247; R/C=147/192 (Clinical Neurology)
Kuo JR,Yen CP,Wu SC,Howng SL,Ai-Li Kwan	Comparison of three measurement methods for basilar artery with neurological changes in rabbits subjecting to experimental subarachnoid hemorrhage Acta Neurochirurgica Suppl (2008) 104: 203–2072007 IF: 1.829; R/C=86/199 (Surgery)
Lin KC,Chou CH,Chang WL,Ke DS,Kuo JR	The Early Response of Mannitol Infusion in Traumatic Brain Injury Acta Neurol Taiwan 2008;17:26-32 (Correspondence, Non-SCI)